Immediate reduction in sweat secretion with electric current application in primary palmar hyperhidrosis.
نویسندگان
چکیده
W e present herein data showing for the first time to our knowledge that dry iontophoresis rapidly induces anhidrosis during current application in individuals with hyperhidrosis. This finding provides a novel experimental model for evaluating treatments of hyperhidrosis and determining their mechanism of action. Tap water iontophoresis, during which the patient’s hands are soaked in shallow pans of tap water, sometimes with drugs added (usually anticholinergic agents), has been in wide use for several decades, although little is known about its mechanism of action. While studying iontophoretic delivery of botulinum toxin to the palms of patients with hyperhidrosis, we noted that dry current alone induced relative palmar anhidrosis.
منابع مشابه
The Effect and Persistency of 1% Aluminum Chloride Hexahydrate Iontophoresis in the Treatment of Primary Palmar Hyperhidrosis
Topical solutions containing aluminum chloride are known to be the first line of therapy for hyperhidrosis. Palmar hyperhidrosis however, is less responsive to aluminum chloride therapy and successful treatment may require 6-8 h application of high concentrations up to 30% that commonly leads to skin irritation. The purpose of this study is to investigate the effect of 30 min iontophoretic appl...
متن کاملThe Effect and Persistency of 1% Aluminum Chloride Hexahydrate Iontophoresis in the Treatment of Primary Palmar Hyperhidrosis
Topical solutions containing aluminum chloride are known to be the first line of therapy for hyperhidrosis. Palmar hyperhidrosis however, is less responsive to aluminum chloride therapy and successful treatment may require 6-8 h application of high concentrations up to 30% that commonly leads to skin irritation. The purpose of this study is to investigate the effect of 30 min iontophoretic appl...
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ورودعنوان ژورنال:
- Archives of dermatology
دوره 147 2 شماره
صفحات -
تاریخ انتشار 2011